RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

6 results for "geroscience"

Z_2_19 Verified Molecular Biology

Z_2_19 — Senolytics & Geroscience: Targeting Cellular Senescence in Aging

Cellular senescence — the irreversible arrest of cell division first described by Leonard Hayflick and Paul Moorhead (1961, Experimental Cell Research) — has emerged as a central mechanism of aging and age-related diseas

senolytics cellular-senescence geroscience aging-biology senescent-cells sasp
S_2_08 Verified Future Technology

S_2_08 — Longevity Science: Senolytics, Telomeres, and Lifespan Extension

Longevity science — the systematic study of biological aging with the goal of extending human healthspan (years of healthy life) and potentially lifespan — has transformed from a fringe pursuit into a mainstream biomedic

longevity aging senescence senolytic telomere telomerase
S_2_20 Verified Future Technology

S_2_20 — Longevity Science & Senolytics

Longevity science — also termed geroscience — aims to understand and intervene in the biological mechanisms of aging to extend human healthspan (years of healthy life) and potentially lifespan. The field has shifted from

longevity senolytics senescence aging rapamycin mTOR
Z_2_10 Verified Molecular Biology

Z_2_10 — Genetics of Aging and Progeria

Aging — the progressive decline in physiological function leading to increased vulnerability to disease and death — has a substantial genetic component: twin studies estimate heritability of human lifespan at ~25–30% (He

aging genetics progeria Hutchinson-Gilford progeria HGPS LMNA lamin A
ZE_3_22 Credible Ethics & Applied Philosophy

ZE_3_22 — Longevity Ethics & Life Extension: Moral Dimensions of Radical Lifespan Enhancement

The prospect of radical life extension — extending human lifespan from the current ~80-year average in developed countries to 150, 500, or even indefinite years through senolytics, gene therapy, organ replacement, AI-dri

longevity-ethics life-extension anti-aging radical-lifespan immortality-ethics geroscience-ethics
S_2_05 Verified Future Technology

S_2_05 — Longevity Research — The Science of Aging, Life Extension, and the Quest for Biological Immortality

Aging — the progressive decline in physiological function leading to increased vulnerability, disease, and death — has transitioned from an accepted inevitability to a legitimate target of biomedical intervention. The fi

longevity aging geroscience Hayflick limit telomere telomerase