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33 results for "drug metabolism" — page 1 of 2
X_5_09 — Pharmacology: The Science of Drugs and Their Actions
Pharmacology — the science of drugs — investigates how chemical substances interact with biological systems to produce therapeutic, toxic, or other effects. The discipline encompasses pharmacokinetics (what the body does
ZF_4_05 — Marine Pharmacology and Drug Discovery
Marine pharmacology explores the ocean's vast biodiversity as a source of bioactive compounds for drug development — a field that has yielded several approved drugs and thousands of promising leads since the pioneering w
Z_2_13 — Pharmacogenomics and Personalized Medicine
Pharmacogenomics — the study of how genetic variation influences drug response — is among the most clinically actionable applications of human genetics. Adverse drug reactions (ADRs) are the 4th–6th leading cause of deat
Z_2_03 — Pharmacogenomics & Ethnobotanical Genetics
Pharmacogenomics — the study of how genetic variation affects drug response — has revealed that enzymes governing drug metabolism, particularly the cytochrome P450 (CYP) superfamily, show extraordinary population-specifi
Z_2_18 — Pharmacogenomics and Precision Medicine
Pharmacogenomics — the study of how genetic variation affects individual responses to drugs — aims to replace the "one-size-fits-all" prescribing model with genotype-guided therapy, selecting the right drug at the right
L_5_03 — Pharmacogenomics and Ancestral Medicine
Pharmacogenomics — the study of how genetic variation influences individual responses to drugs — bridges genetics, pharmacology, and clinical medicine. Humans carry extensive polymorphism in genes encoding drug-metaboliz
S_2_11 — Bioinformatics: Computational Genomics and Drug Discovery
Bioinformatics — the application of computational methods to biological data — has become indispensable to modern biology and medicine, driven by the exponential growth of genomic, transcriptomic, proteomic, and metabolo
X_5_19 — Drug Discovery: From Ethnobotany to Rational Design
Drug discovery is the process by which new therapeutic compounds are identified, developed, and brought to clinical use. The field has evolved through three major paradigms: (1) ethnobotanical/traditional knowledge — mos
X_5_20 — Medical Regulation: Clinical Trials, Drug Safety, and the History of Oversight
Medical regulation — the system of laws, agencies, and protocols governing drug development, clinical trials, and medical device approval — evolved over centuries from virtually no oversight to the elaborate global frame
Z_3_12 — Genetics of Alcohol Metabolism
The genetics of alcohol metabolism provides one of the clearest examples of how specific genetic variants influence behavior and disease risk at a population scale. Ethanol is metabolized primarily through a two-step oxi
Z_2_04 — Genetic Disorders and Inborn Errors of Metabolism
Genetic disorders — diseases caused by mutations in single genes (monogenic) or chromosomal abnormalities — affect ~3–5% of live births and collectively represent thousands of distinct conditions catalogued in the Online
X_3_05 — Antibiotics and Antimicrobial Resistance
Antibiotics — substances that kill or inhibit bacterial growth — represent one of the most transformative medical discoveries in human history, having saved an estimated 200 million+ lives since their introduction. Their
Y_4_21 — Fasting-Induced Altered States
Fasting-induced altered states of consciousness — visionary experiences, euphoria, time distortion, dissociation, and mystical-type experiences produced by prolonged food deprivation — represent one of humanity's oldest
Y_1_16 — Psychedelic Legal Frameworks: Regulation, Decriminalization, and Therapeutic Access
The legal status of psychedelic substances — including psilocybin, LSD, MDMA, DMT/ayahuasca, mescaline, and ibogaine — has undergone dramatic shifts since the mid-20th century, moving from unregulated research compounds
ZE_3_06 — Ethics of Psychedelic Research and Therapy
The ethics of psychedelic research and therapy addresses the unique moral challenges posed by substances that profoundly alter consciousness in therapeutic, religious, and research contexts. After a 40-year research mora
X_5_01 — Venom, Toxicology, and Poison Medicine
Toxicology — the study of the adverse effects of chemical, physical, or biological agents on living organisms — and the medical management of poisoning and envenomation have ancient roots and a rich history intertwining
X_1_07 — Indigenous Pharmacopeias: Validated Compounds
Indigenous peoples have developed sophisticated pharmacopeias over millennia of empirical observation and systematic experimentation — and modern pharmaceutical science has repeatedly validated these knowledge systems. A
X_3_25 — Antibiotic Resistance Crisis
Antimicrobial resistance (AMR) — the ability of microorganisms to survive exposure to drugs that once killed them — is one of the most serious threats to global public health in the twenty-first century. [KEY FINDING] A
ZF_5_10 — Marine Biotechnology: Blue Pharmacy and Ocean Genetic Resources
The ocean harbors an estimated 2.2 million species (most undescribed) across environments spanning freezing polar waters to superheated hydrothermal vents, anoxic sediments to UV-drenched coral reefs — a staggering diver
Z_2_06 — Nutrigenomics and Diet-Gene Interactions
Nutrigenomics — the study of how genetic variation influences nutritional requirements, dietary responses, and disease susceptibility — and its complement nutrigenetics (how diet influences gene expression) represent a r
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