RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

191 results for "alcohol use disorder" — page 1 of 10

Z_3_12 Verified Molecular Biology

Z_3_12 — Genetics of Alcohol Metabolism

The genetics of alcohol metabolism provides one of the clearest examples of how specific genetic variants influence behavior and disease risk at a population scale. Ethanol is metabolized primarily through a two-step oxi

alcohol metabolism ADH1B ALDH2 acetaldehyde Asian flush alcohol dehydrogenase
X_4_15 Verified Medicine & Healing

X_4_15 — Addiction Medicine & Substance Abuse

Addiction medicine is a medical subspecialty formally recognised by the American Board of Medical Specialties (ABMS) in October 2015, though its intellectual roots stretch to Dr. Benjamin Rush's 1784 description of alcoh

addiction medicine substance use disorder opioid epidemic harm reduction mesolimbic pathway dopamine
U_5_17 Credible Art, Music & Culture

U_5_17 — Museum Decolonization: Repatriation, Representation, and the Politics of Display

Museum decolonization — the critical movement to address the colonial origins, structures, and power dynamics embedded in museum collections, exhibition practices, and institutional governance — has become one of the mos

museum decolonization repatriation NAGPRA Benin Bronzes cultural property postcolonial museology
J_3_11 Verified Ancient Technology

J_3_11 — Ancient Lighthouse Technology: Pharos and Navigation Beacons

The Pharos of Alexandria — the lighthouse built on the island of Pharos at the entrance to Alexandria's harbor around 280 BCE under the Ptolemaic dynasty — was one of the Seven Wonders of the Ancient World and the archet

lighthouse Pharos Alexandria beacon navigation fire
T_2_07 Verified Psychology & Social

T_2_07 — Psychology of Addiction

Addiction — compulsive engagement with a substance or behavior despite harmful consequences — is now understood as a chronic brain disorder involving neuroplastic changes in reward, motivation, memory, and executive cont

addiction psychology substance use disorder dopamine reward incentive sensitization tolerance dependence
T_2_20 Verified Psychology & Social

T_2_20 — Personality Disorders: Cluster Analysis and Dimensional Models

Personality disorders (PDs) — enduring patterns of inner experience and behavior that deviate markedly from cultural expectations, are pervasive and inflexible, and cause significant functional impairment — affect approx

personality disorder DSM-5 cluster B borderline narcissistic antisocial
T_2_19 Credible Psychology & Social

T_2_19 — Eating Disorders

Eating disorders (EDs) — including anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and avoidant/restrictive food intake disorder (ARFID) — affect an estimated 9% of the global population over th

eating disorders anorexia nervosa bulimia nervosa binge eating disorder body dysmorphia CBT-E
T_2_17 Verified Psychology & Social

T_2_17 — Depression & Mood Disorders

Major Depressive Disorder (MDD) affects an estimated 280 million people worldwide (WHO, 2023) and is the leading cause of disability globally. The neurobiological understanding of depression has undergone a paradigm shif

depression major-depressive-disorder mood-disorders bipolar serotonin neuroplasticity
L_3_17 Verified Genetics & Origins

L_3_17 — Endogenous Retroviruses (HERVs) in the Human Genome

Human endogenous retroviruses (HERVs) — remnants of ancient retroviral infections that integrated into the germline DNA of human ancestors and have been vertically transmitted through the host genome for millions of year

endogenous retroviruses HERVs HERV-K HERV-W syncytin retroviral integration
Y_4_17 Verified Altered States

Y_4_17 — Sleep Disorders & Parasomnias

Sleep disorders affect an estimated 50–70 million Americans and up to 45% of the global population, encompassing over 80 distinct conditions classified by the International Classification of Sleep Disorders (ICSD-3, 2014

sleep disorders parasomnias narcolepsy sleepwalking REM behavior disorder sleep terrors
Y_1_18 Verified Altered States

Y_1_18 — Addiction Neurochemistry: Reward Circuits, Tolerance & Therapeutic Frontiers

Addiction — now formally termed substance use disorder (SUD, DSM-5) — is a chronic, relapsing brain disorder characterized by compulsive drug seeking despite harmful consequences, affecting approximately 35 million peopl

addiction neurochemistry dopamine-reward mesolimbic-pathway opioid-crisis tolerance-dependence
H_3_12 Credible Suppression & Thesis

H_3_12 — Museum Decontextualization: How Display Distorts Meaning

When an archaeological artifact is removed from its findspot — the soil layer, building, grave, or landscape in which it was deposited — and placed in a museum vitrine, it undergoes a fundamental transformation of meanin

museum display decontextualization exhibition interpretation curation
H_3_10 Verified Suppression & Thesis

H_3_10 — Museum Ethics — Who Owns the Past?

The question of who owns the past — and specifically, who has rightful custody of archaeological objects, cultural artifacts, and human remains — is the central ethical controversy in contemporary museum practice. The de

museum ethics repatriation cultural property NAGPRA Elgin Marbles Parthenon marbles
R_2_12 Verified Biology & Evolution

R_2_12 — Tool Use in Animals: Corvids, Primates, Dolphins, and Cognitive Evolution

Tool use — the employment of an external object to alter the form, position, or condition of another object or organism — was once considered uniquely human, a defining cognitive threshold separating Homo sapiens from al

tool use animal cognition New Caledonian crow chimpanzee dolphin sea otter
W_5_37 Verified World Civilizations

W_5_37 — The House of Wisdom: Baghdad and the Islamic Golden Age of Knowledge

The House of Wisdom (Bayt al-Ḥikma) was a major intellectual institution in Baghdad during the Abbasid Caliphate (est. c. 762 CE), reaching its zenith under Caliph al-Maʾmūn (r. 813–833 CE). While its exact nature — libr

House of Wisdom Bayt al-Hikma Baghdad Islamic Golden Age Abbasid Caliphate translation movement
ZF_2_14 Verified Oceanography

ZF_2_14 — Marine Microbiology: Deep-Sea Viruses and Bacterial Ecology

The deep ocean harbors the largest and most diverse microbial ecosystem on Earth — a vast realm of bacteria, archaea, and viruses that drive global biogeochemical cycles, recycle organic matter, and sustain life in condi

marine microbiology deep-sea viruses bacteriophage marine bacteria viral shunt biogeochemical cycling
Z_2_04 Verified Molecular Biology

Z_2_04 — Genetic Disorders and Inborn Errors of Metabolism

Genetic disorders — diseases caused by mutations in single genes (monogenic) or chromosomal abnormalities — affect ~3–5% of live births and collectively represent thousands of distinct conditions catalogued in the Online

genetic disorder inborn error metabolism Mendelian disease sickle cell cystic fibrosis
K_3_06 Verified Consciousness

K_3_06 — Disorders of Consciousness: Coma, Vegetative State, and Minimal Consciousness

Disorders of consciousness (DoC) — coma, vegetative state (now termed unresponsive wakefulness syndrome/UWS), and minimally conscious state (MCS) — represent some of the most challenging clinical and philosophical proble

disorders of consciousness coma vegetative state UWS unresponsive wakefulness syndrome minimally conscious state locked-in syndrome
K_3_14 Credible Consciousness

K_3_14 — Consciousness in Octopuses and Distributed Nervous Systems

Octopuses (Octopus vulgaris, O. bimaculoides, Abdopus aculeatus, and ~300 other species in order Octopoda) represent perhaps the most profound natural experiment in the evolution of consciousness: they are the most cogni

octopus cephalopod consciousness distributed nervous system invertebrate cognition mollusc
J_4_08 Verified Ancient Technology

J_4_08 — Ancient Refrigeration and Ice Storage — Yakhchāl to Ice Houses

The ability to preserve cold — to store ice, cool water, and refrigerate food — was achieved by ancient civilizations through ingenious engineering solutions that exploited evaporative cooling, radiative cooling, thermal

yakhchāl yakhchal ice house ice pit ancient refrigeration evaporative cooling