RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

7 results for "NMDA antagonist"

Y_1_13 Credible Altered States

Y_1_13 — Xenon Gas and Nitrous Oxide: Anesthetic Gases as Consciousness Probes

Nitrous oxide (N₂O — "laughing gas") and xenon (Xe — a noble gas) are two anesthetic gases that have served as remarkable probes of consciousness — revealing how the manipulation of a single molecule or atom can dissolve

nitrous oxide xenon gas laughing gas William James NMDA antagonist anesthetic

Y_1_11 Verified Altered States

Y_1_11 — Ketamine: Dissociative Anesthetic and Consciousness Explorer

Ketamine is a dissociative anesthetic — first synthesized by Calvin Stevens in 1962 and introduced into clinical use by Edward Domino and Guenter Corssen (1966) — that has undergone a remarkable transformation from battl

ketamine dissociative anesthetic K-hole NMDA antagonist depression esketamine

C_1_20 Credible Global Traditions

C_1_20 — The Shadow Archetype in World Mythology

The Shadow archetype, articulated by Carl Gustav Jung as a fundamental component of the psyche, manifests across world mythologies as the dark double, the rejected brother, or the monstrous other that heroes must confron

shadow-archetype jungian-psychology dark-double mythological-antagonist set-osiris caliban

ZB_2_13 Verified Ecology & Biology

ZB_2_13 — Death Biology: Programmed Cell Death

Death in biology is not merely the passive failure of living systems but an actively regulated process at multiple levels — from individual cells to whole organisms. Programmed cell death (PCD), particularly apoptosis, w

apoptosis programmed cell death necroptosis pyroptosis ferroptosis autophagy

Y_1_17 Verified Altered States

Y_1_17 — Ketamine Therapy and Dissociative Medicine

Ketamine — a dissociative anesthetic synthesized by Calvin Stevens at Parke-Davis in 1962 and first used clinically by Edward Domino and Guenter Corssen in 1966 — has emerged as a revolutionary treatment for treatment-re

ketamine esketamine spravato depression treatment-resistant nmda-receptor

Y_1_19 Credible Altered States

Y_1_19 — Ibogaine Reset Mechanism

Ibogaine — a naturally occurring psychoactive indole alkaloid extracted from the root bark of Tabernanthe iboga, a shrub native to the equatorial forests of Gabon and Cameroon — has emerged as one of the most pharmacolog

ibogaine iboga Tabernanthe iboga addiction opioid noribogaine

R_3_14 Verified Biology & Evolution

R_3_14 — Evolution of Aging and Senescence

Aging — the progressive decline in physiological function and increase in mortality rate with time — is one of evolution's deepest puzzles: why would natural selection, which optimizes fitness, permit organisms to deteri

aging senescence evolution mutation accumulation antagonistic pleiotropy disposable soma

BROWSE BY SECTION — 3,721 documents across 34 fields

A Foundations 112 Docs B Beings & Entities 114 Docs C Global Traditions 116 Docs D Sites & Artifacts 116 Docs E Cataclysms & Chronology 109 Docs F Lost Connections 111 Docs G Modern Frameworks 99 Docs H Suppression & Thesis 95 Docs I UAP Disclosure 87 Docs J Ancient Technology 103 Docs K Consciousness 105 Docs L Genetics & Origins 92 Docs M Forbidden Archaeology 103 Docs N Secret Societies 87 Docs O Earth Anomalies 108 Docs P Philosophy & Meaning 104 Docs Q Cosmology & Physics 100 Docs R Biology & Evolution 95 Docs S Future Technology 100 Docs T Psychology & Social 112 Docs U Art, Music & Culture 122 Docs V Mathematics & Information 87 Docs W World Civilizations 140 Docs X Medicine & Healing 126 Docs Y Altered States 108 Docs Z Molecular Biology 112 Docs ZA Physics & Quantum 117 Docs ZB Ecology & Biology 117 Docs ZC Social Science 111 Docs ZD Information & Computation 96 Docs ZE Ethics & Applied Philosophy 99 Docs ZF Oceanography 105 Docs ZG Linguistics & Communication 110 Docs ZH Archaeoastronomy 114 Docs