RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

5 results for "CAR-T"

X_3_28 Verified Medicine & Healing

X_3_28 — Cancer Immunotherapy Revolution

Cancer immunotherapy — harnessing the body's own immune system to recognize and destroy tumor cells — has transformed oncology from a field dominated by surgery, radiation, and chemotherapy into one where the immune syst

cancer immunotherapy checkpoint inhibitor PD-1 PD-L1 CTLA-4 CAR-T

X_4_01 Verified Medicine & Healing

X_4_01 — Personalized and Genomic Medicine

Personalized medicine (also called precision medicine) represents the shift from one-size-fits-all treatment to therapies tailored to an individual's genetic profile, biomarkers, and molecular disease characteristics. Th

personalized medicine precision medicine pharmacogenomics gene therapy CRISPR therapeutics biomarker

X_3_18 Verified Medicine & Healing

X_3_18 — Immunotherapy: From Coley's Toxins to Checkpoint Inhibitors

Immunotherapy — harnessing the immune system to fight cancer and other diseases — was pioneered by William Coley (Memorial Hospital, New York), who injected bacterial toxins into inoperable sarcomas beginning in 1891 and

immunotherapy checkpoint inhibitor PD-1 CTLA-4 CAR-T cancer immunology

Z_5_01 Verified Molecular Biology

Z_5_01 — CRISPR Applications and Genetic Engineering

CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology adapted from a bacterial immune defense system, enabling precise, programmable modification of DNA in vir

CRISPR Cas9 gene editing genetic engineering CRISPR-Cas9 guide RNA

Z_2_05 Verified Molecular Biology

Z_2_05 — Gene Therapy: History and Progress

Gene therapy — the introduction, alteration, or replacement of genetic material within a patient's cells to treat or cure disease — has evolved from a speculative concept to an approved clinical reality over five decades

gene therapy gene replacement viral vector adeno-associated virus AAV lentivirus

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